Phenergan Elixir 5mg/5ml Oral Solution - 100ml

Phenergan Elixir 5mg/5ml Oral Solution - 100ml
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Phenergan Elixir 5mg/5ml Oral Solution - 100ml

To treat allergic conditions. To prevent travel sickness. To treat adult insomnia.


Phenergan Elixir 5mg/5ml Oral Solution - 100ml

To treat allergic conditions. To prevent travel sickness. To treat adult insomnia. Orange Flavour

Main use

Active ingredientManufacturer

Allergies, travel sickness

Promethazine hydrochloride

Sanofi-Aventis

How does it work?

Phenergan tablets and elixir contain the active ingredient promethazine, which is a type of medicine called a sedating antihistamine. It works by preventing the actions of histamine.

Histamine is a substance produced by the body as part of its defence mechanisms. It causes the symptoms of allergic reactions. These can include inflammation of the airways or skin, nasal congestion, narrowing of the airways, rashes, and itching of the skin, eyes or nose. Promethazine blocks histamine from binding to its receptors in various parts of the body and this stops it causing the symptoms of an allergic reaction.

Histamine may be released from and act in a small (localised) area of the body such as the nose. Alternatively, histamine can cause more serious, sometimes life-threatening reactions such as anaphylaxis. Promethazine is used for treating localised allergies such as hay fever and nettle rash, as well more serious allergic reactions such as anaphylaxis.

Promethazine also blocks histamine receptors in an area of the brain called the vomiting centre. The vomiting centre is responsible for causing feelings of sickness and for the vomiting reflex. It is activated when it receives nerve messages from the vestibular apparatus in the middle ear.

The vestibular apparatus provides constant feedback to the brain about our body position. When something disturbs the vestibular apparatus, such as movements of the head when travelling by boat or car, nerve signals are sent from the vestibular apparatus to the vomiting centre. This can cause the symptoms of motion sickness, such as nausea, dizziness or spinning sensations (vertigo) and vomiting. Promethazine can be used to prevent motion sickness, because by blocking the histamine receptors in the vomiting centre, it prevents disturbances in the middle ear from activating the vomiting centre.

Promethazine is known as a sedating antihistamine because it enters the brain in significant quantities and causes drowsiness. This effect of the medicine is used to produce sedation before minor procedures or surgery, and can also be used to provide short-term help for people with sleeping difficulties (insomnia).

What is it used for?

  • Allergic conditions such as hay fever (allergic rhinitis) and nettle rash (urticaria).
  • Life threatening allergic reactions (anaphylaxis).
  • Preventing travel sickness.
  • Sedation before surgery (preoperative sedation).
  • Short-term use as a sedative in children.
  • Short-term treatment of sleeping difficulties (insomnia) in adults.

Warning!

  • This medicine should not be used for longer than seven days without seeking medical advice from your doctor.
  • This medicine may cause drowsiness that can last up to 12 hours. If affected you should not perform potentially hazardous tasks such as driving or operating machinery. You should avoid drinking alcohol because it is likely to make any drowsiness worse.
  • This medicine may make your skin more sensitive to sunlight than it usually is, so you should avoid exposing your skin to direct sunlight or sunlamps until you know how your skin reacts. If you can't avoid strong sunlight you should use a sunscreen lotion or make sure your skin is protected with clothing.
  • This medicine may interfere with some pregnancy tests, causing false negative or false positive results.
  • If you are due to have any skin prick tests to diagnose allergies you should stop taking this medicine at least 72 hours before the tests. This is because antihistamines can prevent or lessen the skin reactions that indicate an allergy, and so can make the test results unreliable.
  • Phenergan elixir should not be used if the bottle has been open for more than a month. You may find it helpful to write the date you open the bottle on the label. Any syrup remaining in the bottle after it has been open for a month should be carefully disposed of, preferably by returning to your pharmacy.

Use with caution in

  • Elderly people.
  • Decreased kidney function.
  • Decreased liver function.
  • Asthma.
  • Bronchitis.
  • A condition called bronchiectasis in which there is persistent and progressive widening of the airways due to lung infections or lung disease, such as cystic fibrosis.
  • Severe coronary artery disease (heart disease).
  • Closed angle glaucoma.
  • Epilepsy.
  • Blockage of the opening from the stomach into the intestines (pyloro-duodenal obstruction).
  • Blockage of the drainage of urine out of the bladder (bladder neck obstruction), for example due to an enlarged prostate gland.

Not to be used in

  • Children under two years of age.
  • Reduced awareness, slow reactions or extreme drowsiness due to medicines or illness that reduce activity in the central nervous system (CNS depression).
  • Comatose states.
  • People who have taken a type of medicine called a monoamine oxidase inhibitor (MAOI) in the past 14 days.
  • This medicine should be avoided in children and adolescents with signs and symptoms suggestive of Reye's Syndrome.
  • Phenergan tablets contain lactose and should not be taken by people with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption.
  • Phenergan elixir contains glucose syrup and is not suitable for people with diabetes or rare hereditary problems of fructose intolerance.

This medicine should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy.

If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately.

Pregnancy and breastfeeding

Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine.

  • If you are pregnant you should not take this medicine without consulting your doctor first. This medicine can be used with caution during pregnancy, but only if the expected benefit to the mother outweighs any potential risks to the developing baby. However, this medicine should not be used during the last two weeks of a pregnancy, because if taken during this time it may cause irritability or excitement in the baby after birth. Seek further medical advice from your doctor.
  • Small amounts of this medicine may pass into breast milk. This is not expected to be harmful to a nursing infant, but the manufacturer states that there is a risk that it may cause irritability or excitement in a newborn baby. If you are breastfeeding you should not take this medicine without seeking medical advice from your doctor first.

Label warnings

  • This medication may cause drowsiness. If affected do not drive or operate machinery. Avoid alcoholic drink.

Side effects

Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Just because a side effect is stated here does not mean that all people using this medicine will experience that or any side effect.

  • Drowsiness.
  • Dizziness.
  • Restlessness.
  • Headache.
  • Nightmares.
  • Tiredness.
  • Blurred vision.
  • Difficulty passing urine (urinary retention).
  • Dry mouth.
  • Confusion.
  • Unexpected increase in excitability in children.
  • Rash or itching.
  • Loss of appetite.
  • Awareness of your heartbeat (palpitations).
  • Low blood pressure (hypotension).
  • Abnormal movements of the hands, legs, face, neck and tongue, eg tremor, twitching, rigidity (extrapyramidal effects).
  • Blood disorders.
  • Increased sensitivity of the skin to sunlight (photosensitivity). If affected you should avoid sun lamps and direct sunlight while you are taking this medicine.

The side effects listed above may not include all of the side effects reported by the drug's manufacturer.

For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.

How can this medicine affect other medicines?

It is important to tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you start taking this medicine. Similarly, check with your doctor or pharmacist before taking any new medicines while taking this one, to ensure that the combination is safe.

The manufacturer states that this medicine should not be taken by anyone who is taking a type of antidepressant called a monoamine oxidase inhibitor (MAOI), eg phenelzine, tranylcypromine, isocarboxazid, or who has taken an MAOI in the previous 14 days.

There may be an increased risk of drowsiness if this medicine is taken with any of the following (which can also cause drowsiness):

  • alcohol
  • antipsychotic medicines, eg chlorpromazine
  • barbiturates, eg phenobarbital
  • benzodiazepines, eg diazepam, temazepam
  • sedating antihistamines, eg chlorphenamine, brompheniramine, hydroxyzine
  • sleeping tablets, eg zopiclone
  • strong opioid painkillers, eg morphine, codeine, dihydrocodeine
  • tricyclic antidepressants, eg amitriptyline.

There may be an increased risk of side effects such as dry mouth, constipation, difficulty passing urine or confusion if promethazine is taken with other medicines that have anticholinergic effects, such as the following:

  • anticholinergic medicines for Parkinson's symptoms, eg procyclidine
  • antispasmodic medicines, eg hyoscine
  • certain antihistamines, eg brompheniramine, chlorphenamine
  • certain antipsychotic medicines, eg chlorpromazine
  • certain antisickness medicines, eg prochlorperazine, meclozine, cyclizine
  • medicines for urinary incontinence, eg oxybutynin, flavoxate, tolterodine, propiverine, trospium
  • muscle relaxants, eg baclofen
  • MAOI antidepressants, eg phenelzine
  • tricyclic antidepressants, eg amitriptyline.

This medicine may oppose the effect of betahistine.

 

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   This Product is Pharmacy Only [P] and can only be sold under the supervison of a pharmacist.

   You will be required to answer a few basic questions during the checkout process which be reviewed by our pharmacist to ensure that the product is suitable for use.

We are a UK Registered Pharmacy regulated by the GPhC - General Pharmecutical Council.  

PLEASE NOTE: Regulations Prohibit the sale of Pharmacy Only Items Outside of the UK.

Some products marked as pharmacy only items may be subject to age restrictions and may not be suitable for use by everyone.

Always read the label or patient information leafet before taking any medication and if you are unsure speak to your pharmacist.

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