Buscopan IBS Relief Buscopan IBS Relief relieves abdominal cramps which cause pain and discomfort in irritable bowel syndrome. It works by an antispasmodic effect, relaxing the cramping muscle of your bowel. Dosage: Only take Buscopan IBS Relief if your doctor has diagnosed that you have irritable bowel syndrome. Adults and children over 12 years of age: Start by taking one tablet 3 times a day. If more relief is needed, you can increase your dose to a maximum of two tablets 4 times a day. Swallow the tablet whole with water. Main use Active ingredient Manufacturer Irritable bowel syndrome Hyoscine butylbromide Boehringer Ingelheim Limited How does Buscopan IBS Relief work? Buscopan IBS relief tablets contain the active ingredient hyoscine butylbromide, which is a type of medicine called an antispasmodic. It can be bought without a prescription to relieve painful spasms and cramps associated with irritable bowel syndrome that has previously been diagnosed by a doctor. Hyoscine works by relaxing the muscle that is found in the walls of the stomach, intestines and bile duct. This type of muscle is called smooth muscle or involuntary muscle. It normally contracts and relaxes in response to natural body chemicals called neurotransmitters. The contractions are caused by a neurotransmitter called acetylcholine. These contractions are not under our conscious control and we are not normally aware of them. However, if the muscles go into spasm this can cause pain. Hyoscine stops the spasms in the smooth muscle by preventing acetylcholine from acting on the muscle. It does this by blocking the receptors on the muscle cells that the acetylcholine would normally act on. By preventing acetylcholine from acting on the muscle in the GI tract, hyoscine reduces the muscle contractions. This allows the muscle to relax and reduces the painful spasms and cramps. What is Buscopan IBS Relief used for? Spasms of the stomach or intestine, associated with irritable bowel syndrome (IBS) that has previously been diagnosed by a doctor. Warning! You should only take Buscopan IBS relief if your doctor has already diagnosed you with irritable bowel syndrome. Even if your doctor has diagnosed your IBS, you should not take this medicine without first discussing it with your doctor if any of the following apply to you: you are 40 years or over and it is some time since your last attack of IBS or the symptoms are different this time; you have recently passed blood from the bowel; you suffer from severe constipation; you are feeling sick or vomiting; you have lost your appetite or lost weight; you have difficulty or pain passing urine; you have a fever; or you have recently travelled abroad. Consult your doctor if your symptoms change or get worse, or have not improved after 14 days of treatment with this medicine. This medicine may cause blurred vision and so may affect your ability to drive or operate machinery safely. If affected do not drive or operate machinery. You should consult your doctor immediately if you experience any of the following while using this medicine: red and painful eye, possibly with headache, loss of vision or blurred vision, or seeing haloes around lights. These symptoms may be caused by an increase in pressure inside the eyeball and require urgent investigation by your doctor. Use with caution in Elderly people. Fast heart rate (tachycardia). Heart Failure. Thyrotoxicosis. People susceptible to blockage of the urinary tract and difficulty passing urine, for example men with an enlarged prostate gland. People susceptible to blockage of the intestines. Fever (pyrexia). Not to be used in Abnormal muscle weakness . Abnormally large or dilated large intestine (megacolon). Closed angle glaucoma. Hereditary blood disorders known as porphyrias. Rare hereditary problems of fructose intolerance, glucose-galactose malabsorption or sucrase-isomaltase insufficiency (Buscopan IBS relief tablets contain sucrose). Buscopan IBS relief tablets are not recommended for children under 12 years of age. This medicine should not be used if you are allergic to any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy. If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately. Pregnancy and breastfeeding Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine. If you are pregnant or trying for a baby you should not use this medicine without consulting your doctor first. This medicine should be used with caution during pregnancy, and only if the expected benefit to the mother is greater than the possible risk to the foetus, particularly in the first trimester. Seek medical advice from your doctor. It is not known if this medicine passes into breast milk. If you are breastfeeding you should consult your doctor before using this medicine. It should be used with caution in nursing mothers, and only if the benefits to the mother outweigh any risks to the nursing infant. Discuss this with your doctor. Side effects Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Just because a side effect is stated here does not mean that all people using this medicine will experience that or any side effect. Uncommon (affect between 1 in 100 and 1 in 1000 people) Increase in heart rate (tachycardia). Dry mouth. Reduced ability to sweat. Allergic skin reactions. Rare (affect between 1 in 1000 and 1 in 10,000 people) Difficulty in passing urine (urinary retention). Hypersensitivity reactions such as narrowing of the airways (bronchospasm), swelling of the lips, throat and tongue (angioedema), or itchy rash. Unknown frequency Anaphylactic reaction or shock. The side effects listed above may not include all of the side effects reported by the medicine’s manufacturer. For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist. How can Buscopan IBS Relief affect other medicines? It is important to tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you start treatment with this medicine. Similarly, check with your doctor or pharmacist before taking any new medicines while taking this one, to ensure that the combination is safe. There may be an increased risk of anticholinergic side effects, such as dry mouth, blurred vision, constipation and difficulty passing urine, if this medicine is taken with other medicines that have anticholinergic effects, such as the following: other antispasmodics, eg atropine, propantheline, dicycloverine antihistamines, eg promethazine, brompheniramine, chlorphenamine, diphenhydramine, triprolidine antisickness medicines, eg meclozine, cyclizine, hyoscine hydrobromide antimuscarinic medicines for Parkinson’s symptoms, eg procyclidine, orphenadrine, trihexiphenidyl antimuscarinic medicines for urinary incontinence, eg oxybutynin, trospium, tolterodine antiarrhythmics, eg disopyramide, propafenone, quinidine tricyclic antidepressants, eg amitriptyline, clomipramine antipsychotics, eg chlorpromazine, clozapine, thioridazine muscle relaxants, eg baclofen amantadine. If this medicine is taken with domperidone or metoclopramide the actions of the medicines may cancel each other out. This is because metoclopramide and domperidone increase the motility of the gut, whereas hyoscine reduces it. If you experience a dry mouth as a side effect of this medicine you may find that medicines that are designed to dissolve and be absorbed from under the tongue, eg sublingual glyceryl trinitrate tablets, become less effective. This is usually because the tablets do not dissolve properly in a dry mouth. To resolve this, have a drink of water before taking tablets designed to dissolve on or underneath the tongue.